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In this article, we clearly show that conolidine, a normal analgesic alkaloid used in common Chinese medication, targets ACKR3, thereby furnishing extra evidence of the correlation amongst ACKR3 and soreness modulation and opening alternate therapeutic avenues for that therapy of Persistent suff

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[4] Molecular and pharmacological components of piperine as a possible molecule for illness prevention and administration: evidence from clinical trials "We verified that conolidine binds to your freshly identified opioid receptor ACKR3, even though displaying no affinity for one other f